Dapsone-induced Haemolysis

Acne fulminans with dapsone induced haemolysis: a case report.

124 was seen at the Dermatology Clinic, University Hospital, Kuala Lumpur. Physical examination showed a healthy young female with severe pustular acne on her forehead and cheeks (Fig. 1l. There was no fever or arthralgia. Due to her poor response to the oral tetracycline prescribed previously by her doctor, she was started on oral dapsone 1OO/mg dai ly and advised to wash her face with 1% cetr...

Dapsone induced eosinophilic pneumonia.

Eosinophilic lung diseases (ELD) are a variety of several clinical entities, which may result from different etiologies, including drug treatment. Dapsone, a sulfone antibiotic widely used in leprosy (among other indications), has been described as a possible cause of ELD. We report a patient with leprosy who presented with respiratory symptoms and pulmonary infiltrates and was diagnosed as suf...

Methane-induced haemolysis of human erythrocytes.

Human erythrocytes were exposed to high concentrations of methane and nitrogen through the application of elevated partial pressures of these gas molecules. Cell leakage (haemolysis) was measured for cells exposed to these gases under a wide range of experimental conditions. Application of methane produces haemolysis at pressures far below the hydrostatic pressures known to disrupt membrane or ...

Hemolysis and Anemia Induced by Dapsone Hydroxylamine

Dapsone-induced erythroderma with Beau's lines.

A 35-year-old female with borderline lepromatous (BL) leprosy who suffered from dapsone-induced erythroderma is reported. Sudden onset of erythroderma gave rise to a temporary arrest of the function of nail matrix with the resultant Beau's lines. She rapidly recovered with omission of dapsone and therapy with systemic corticosteroids and a topical emollient. In view of the potentially fatal hyp...